Thermo Scientific^? Acclaim^? Trinity^? Q1 columns are unique, high-efficiency, silica-based columns designed for the separation of the herbicides diquat and paraquat. These quaternary amines are widely used as nonselective contact herbicides. Due to their toxicity, they are monitored in drinking water and wastewater for agricultural exposure. The Acclaim Trinity Q1 columns can quickly and easily separate these compounds. The separation is compatible with mass spectrometry detection, which significantly improves sensitivity for the analytes and provides conformation at the same time.

Column features include:

• Excellent resolution of diquat and paraquat
• Good peak shape
• Fast analysis
• LC/MS compatibility
• No ion-pairing reagent needed
• Ease of use

This new column, based on Nanopolymer Silica Hybrid (NSH) technology, provides multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The chromatography can be easily optimized by adjusting mobile phase buffer concentration, pH, and solvent content, concurrently or independently. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

Nano Silica Hybrid (NSH) Chromatographic Features

• Multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by mobile phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagent